Utility of Nuclear Morphometry in Effusion Cytology
نویسندگان
چکیده
منابع مشابه
Utility of Nuclear Morphometry with ImageJ in Effusion Cytology
An effusion denotes pathological accumulation of fluids in the serous cavities resulting from several nonneoplastic and neoplastic causes. Cytological diagnosis of effusion fluids is an important investigation to determine the appropriate treatment.The distinction of reactive mesothelial cells from carcinoma cells can sometimes prove to be a diagnostic challenge even for the experienced cytopat...
متن کاملDetection of malignant mesothelioma using nuclear structure of mesothelial cells in effusion cytology specimens.
Mesothelioma is a form of cancer generally caused from previous exposure to asbestos. Although it was considered a rare neoplasm in the past, its incidence is increasing worldwide due to extensive use of asbestos. In the current practice of medicine, the gold standard for diagnosing mesothelioma is through a pleural biopsy with subsequent histologic examination of the tissue. The diagnostic tis...
متن کاملUtility of cytology microarray constructed from effusion cell blocks for immunomarker validation.
BACKGROUND Tissue microarray allows rapid and efficient evaluation of gene expression at the protein level and of immunochemical markers. To our knowledge, there has been no report of constructing cytology microarray using effusion cell blocks and testing its utility in immunochemical marker validation. METHODS A total of 23 malignant effusions (primary tumor of breast [5], GI tract [5], lung...
متن کاملUtility of Nuclear Morphometry in Predicting Grades of Diffusely Infiltrating Gliomas
Introduction. The ability to reliably differentiate neoplastic from nonneoplastic specimen and ascertain the tumour grade of diffusely infiltrating gliomas (DIGs) is often challenging. Aims and Objective. To evaluate utility of image morphometry in identifying DIG areas and to predict tumour grade. Materials and Methods. Image morphometry was used to analyze the following nuclear features of 30...
متن کاملDiagnostic DNA-Flow- vs. -Image-Cytometry in Effusion Cytology
AIMS To determine the sensitivity and specificity of flow- and image-cytometry for the detection of DNA-aneuploidy as a marker for malignant cells in effusions. METHODS 200 effusions (80 tumor cell-positive, 74 negative and 46 cytologically equivocal) were stained with DAPI-SR for DNA-flow- and with Feulgen-Pararosaniline for -image-cytometry. They were measured using a PAS-flow-cytometer and...
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ژورنال
عنوان ژورنال: Asian Pacific Journal of Cancer Prevention
سال: 2014
ISSN: 1513-7368
DOI: 10.7314/apjcp.2014.15.16.6919